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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5910e3b16bd1716e43715d9d048d587cebe2f7147a0ca8f6b5f788906ebfaece' 
  AND token = '8S7fgQ5A01b00a8eoIa8uwWlejhtgBQR53iugC/m9bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}