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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22eb72d7c371c11e2b0e4350e2b74f386569937b2b7d6b858c4d2f8f3f4d3fd4' 
  AND token = 'ejj1C9ilecBj1/hvqCIz4emIm2X44/kZw7MfnBaIr5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}