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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e621237edda59b9290d5ad92866aa692660d069f3eb058b5ecffe7c7784a93ca' 
  AND token = 'XowdeJ7ZjMF0l1sFD9SbLhVdE6B2rLXZiyW99ahkAOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}