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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bb5ce4ccc2d64aa4f434123f842e0dddcd8aad3df0287575ae73abe53d324d6' 
  AND token = 'X5F1a/gFLO/YPjSwHxBSc0IfZJQs/TsBs/r7WMdLPzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}