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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfe0b4bf3f1fab0da7a6592cd25f0b40ac331c17feb5edae3cf2eef2a5777be6' 
  AND token = '4miZfdUGjsE3ZWumJk9xfNQ9QH1EUGu5SQLCjVD4CPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}