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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef667d11fdfbc19d287093ec8ede35cc4b0f3b079df1d042856127eeb5391440' 
  AND token = 'oV+txQbjbaFtjfqe24dTXW0/J0OuDdYqg5hrAVy9w0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}