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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0073ef81a5dc2e53efe2aaedc7c5261314be534732d3e3cdb04c1d58d731ea6f' 
  AND token = 'jn+cgaXKsPkmpis9i6iacR1OZopVW6PVfWs8JRCo5+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}