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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd80855cd4ded52b9ff57ac530bf1f01916de1e998a4785b30a6f77a8d0d69909' 
  AND token = 'D3NMluM0BVk4bhGilYM1+EJWRcAuoCJT2/48V8FH0RI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}