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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a59cc0d652be8d15a479d2681b6a205ee4dca89c8805049ec55c81b1ed1bb8bc' 
  AND token = 'CUuDtxYol+c6qeHC9Yrv32zV7BHiTpXaDawVP3wYY0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}