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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7487bc26bd2cd89d93ea97865d935bbd2b4b8cbabb216f2aec8026a74853d266' 
  AND token = '+yMOCwN1yn1LQb3fQxmTH/VDfxXCXUe9jCuHLNGVQ4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}