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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed7fcf18ad0b2283276019ab9df26ba0970b02131dfbe9768fe7715012fa91b' 
  AND token = '4QbKK8WRmbBQ7qDpVS415TjHS7pXGJJbpAPDizy7ins=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}