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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b20a567e7d37887045c83d0daf857dc8433cf6434b51b6c0c514ea619d3873c4' 
  AND token = 'SNG9Gnt/gD/rUCt0Z6DL0OYPrHfqrbLWT6fUmM5MUhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}