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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b8c00dbf621330efc5420152df21448bf97398360cad11a97ef93c1485e0c9' 
  AND token = 'xeVILvMS56IQt10nplzMdx4jCtYkn64quMXP07hgaJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}