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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1848b6763d7ae693c23d0ede2507db6f9945f9bcda43f125baf510346215bb66' 
  AND token = 'i8njm4Ckbb6MbYDFY4AGDs+RRHggPFtwB4B8ixUsZg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}