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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d39448850c070e460d3dfb9d945b1d95fe473c4ac5566e5eeb3ee5b0db09bc4' 
  AND token = 'vRoTqSSEnQRaflx14tm9dcbDQSjk5rjrE6mM2O7/M9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}