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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2b41d262b1b22fc308814c45ea01109d8904cdbf9a080145fa68e412af3490c' 
  AND token = 'PaJhmtdSSW0Q3+VeLe8DNVDCAwVR2G1hCWTQueGa8GE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}