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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b75bb31325747358f7d3a8cfd3c76f993f4fae1624e5a738f08a4fef7de243a' 
  AND token = 'U4QVkuwvAS+hhLtfFHLOAfowg99Rrp+mM2B+uh8c1NY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}