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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1889312219f0e2193f0d46aaf03db0e41d5a7ce15121c112a99dc4e6a3d0eaec' 
  AND token = 'LBDr12dv7Ta9Ru2m71Zae+XkPOf3WD5kfuSemT8D6Lw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}