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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5419b6cdd82270e78bf1a844b94fd5a75fb91d7377856788e87458909b13cbfe' 
  AND token = 'qZCj+idjF9AfZz61DCQRbVysKRp1oDSr//sFNZFks7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}