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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48e956f43d0eedae55d2163a32ab6daf6f423170d1f0ff8d2e1d34bbbc620bd9' 
  AND token = 'FRg4RyeTHqNKmVr8E2bmS+K8PS4DjR9LTmKb5LdDg8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}