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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '215c50a27e3ccc6278eb94818509b40dcc02ef766b508358f57032e37c348db4' 
  AND token = 'OY14kn+L4gl+iv6JduY6aCIYTA1wgLiwdUBeTKGCLlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}