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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a21d06cf4836f9da60240876b75c8ae6f1b4c14089a4358e8dd9cc8a72bf6322' 
  AND token = 'YulJBdpRbb2qlTS+4idkWUo16baCmx0Ua8GbaMf7zjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}