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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b8363be0b95c73c20cad2c5f8f93e25979cd4ec646b2a4eecacaf05a5da39a4' 
  AND token = 'TcofOXUcxjuCpXqf3rRx9NTCwd9iB+/nc5Sxm/udNl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}