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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8801a21523586fa340f05aaa6ae34af0d017ac0a006f625b2f94895b89f6cd2c' 
  AND token = '0gR4lY/Niy2IqsWFWy9vwsBI/HFpO5JTrUlcQgUqkZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}