SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81bd6db2d2a5072f5f4be2bbec74c50dafb49af2a3784f98a7709488b174af45' 
  AND token = 'zXubU6VL6eRml0gnO17ghH/p0UjI6SDB9sd6jvZ/peM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}