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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43916d41f683ce49f890683a7d3189edea0eb9b9b12765476f4658d2a5d96b4b' 
  AND token = '00Ix3PoFKVJ9TsP5tCkGWgWh+kSKk2N8ftW/M927Dcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}