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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad9b4eba225679540cbb6b3f411da7e4ab1e3706d87a2dfa649c4a8d4909ab36' 
  AND token = 'TTnCOXy9ZBYpdmjqN+NRW3kl7Ilesvbb7UOl8ka+yCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}