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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b066655c76941db2bca02694166e28084e413840b22c7a67af756b9c0b2729b' 
  AND token = 'R2UUWeBx+uOM1acK7BZEKBgfy2AgLzscN3LY+2HVDJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}