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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b4d2f28ef524ccc44fdb3b92956bf9fcc13810624a7ce33e6d13f3c05ba3250' 
  AND token = 'FXTPHjFzTflXN+Z7KNl+fWoX25mkl82gZjoTgBvj17M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}