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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66fd7ddf58f2aa9cd8009fa68726f0e1ffa82069059f0946b336b658bf5df7ed' 
  AND token = 'sKSgIOLD3dUwivMOHv4vrnh0tsaXPM+THPvZ28W60+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}