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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3d750a960f55264ef4fd88ce37d7c6ad3a5f4f83453cf57d1b196a3ec69eba5' 
  AND token = 'ZnIebhvLJa8dFYEH7VfTd6LXQtU/N3sjSpcue2VOjc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}